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Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes.
Antibodies binding to a large subset of T-cell differentiation antigens, including CD2, CD4, CD5, CD6, CD7, CD8, Tp44, and CDw18, cause an increase in the cytoplasmic calcium concentration [( Ca2+]i) after the antigens are crosslinked on the cell surface. Similar crosslinking-induced signals were se...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1987
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3103134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.5.1384 |
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