Ablation of Tumor Progression Locus 2 Promotes a Type 2 Th Cell Response in Ovalbumin-Immunized Mice

The protein kinase encoded by the Tpl2 proto-oncogene regulates ERK activation and cytokine gene expression in macrophages in response to LPS and TNF-. In this study we show that OVA-immunized Tpl2(−/−) mice express high levels of IgE and develop more severe bronchoalveolar eosinophilic inflammation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Watford, Wendy T., Wang, Chun-Chi, Tsatsanis, Christos, Mielke, Lisa A., Eliopoulos, Aristides G., Daskalakis, Constantine, Charles, Nicolas, Odom, Sandra, Rivera, Juan, O’Shea, John, Tsichlis, Philip N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044327/
https://ncbi.nlm.nih.gov/pubmed/19955521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803730
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados