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Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB

Reduced host cell reactivation (HCR) of a reporter gene containing 8-oxoguanine (8-oxoG) lesions in Cockayne syndrome (CS) fibroblasts has previously been attributed to increased 8-oxoG-mediated inhibition of transcription resulting from a deficiency in repair. This interpretation has been challenge...

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Detalhes bibliográficos
Main Authors: Leach, Derrik M., Rainbow, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044198/
https://ncbi.nlm.nih.gov/pubmed/21059811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geq096
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