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Delivery of Plasmid DNA Encoding Bone Morphogenetic Protein-2 with a Biodegradable Branched Polycationic Polymer in a Critical-Size Rat Cranial Defect Model

This study investigated the delivery of plasmid DNA (pDNA) encoding bone morphogenetic protein-2 in the form of polyplexes with a biodegradable branched triacrylate/amine polycationic polymer (TAPP) that were complexed with gelatin microparticles (GMPs) loaded within a porous tissue engineering scaf...

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Detalhes bibliográficos
Main Authors: Chew, Sue Anne, Kretlow, James D., Spicer, Patrick P., Edwards, Austin W., Baggett, L. Scott, Tabata, Yasuhiko, Kasper, F. Kurtis, Mikos, Antonios G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044067/
https://ncbi.nlm.nih.gov/pubmed/20964581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0496
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