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Altering Amine Basicities in Biodegradable Branched Polycationic Polymers for Non-Viral Gene Delivery

In this work, biodegradable branched polycationic polymers were synthesized by Michael addition polymerization from different amine monomers and the triacrylate monomer trimethylolpropane triacrylate. The polymers varied in the amount of amines that dissociate in different pH ranges, which are consi...

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Autors principals: Chew, Sue Anne, Hacker, Michael C., Saraf, Anita, Raphael, Robert M., Kasper, F. Kurtis, Mikos, Antonios G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842827/
https://ncbi.nlm.nih.gov/pubmed/20170180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm901147k
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