Biodegradable Gelatin Microparticles as Delivery Systems for the Controlled Release of Bone Morphogenetic Protein-2

This work evaluated gelatin microparticles and biodegradable composite scaffolds for the controlled release of bone morphogenetic protein-2 (BMP-2) in vitro and in vivo. Gelatin crosslinking (10 and 40 mM glutaraldehyde), BMP-2 dose (6 and 60 ng BMP-2 / mg dry microparticles), buffer type (phosphate...

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Hauptverfasser: Patel, Zarana S., Yamamoto, Masaya, Ueda, Hiroki, Tabata, Yasuhiko, Mikos, Antonios G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018807/
https://ncbi.nlm.nih.gov/pubmed/18474452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2008.04.002
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