Chronic intermittent hypoxia induces lung growth in adult mice

Obstructive sleep apnea (OSA) increases cardiovascular morbidity and mortality, which have been attributed to intermittent hypoxia (IH). The effects of IH on lung structure and function are unknown. We used a mouse model of chronic IH, which mimics the O(2) profile in patients with OSA. We exposed a...

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Detalhes bibliográficos
Main Authors: Reinke, Christian, Bevans-Fonti, Shannon, Grigoryev, Dmitry N., Drager, Luciano F., Myers, Allen C., Wise, Robert A., Schwartz, Alan R., Mitzner, Wayne, Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043819/
https://ncbi.nlm.nih.gov/pubmed/21131398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00239.2010
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