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Intermittent and sustained hypoxia induce a similar gene expression profile in human aortic endothelial cells

Obstructive sleep apnea may cause vascular inflammation and atherosclerosis, which has been attributed to intermittent hypoxia (IH). Recent data suggest that IH, but not sustained hypoxia (SH), activates proinflammatory genes in HeLa cells. Effects of IH and SH on the gene expression profile in huma...

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Bibliografiske detaljer
Main Authors: Polotsky, Vsevolod Y., Savransky, Vladimir, Bevans-Fonti, Shannon, Reinke, Christian, Li, Jianguo, Grigoryev, Dmitry N., Shimoda, Larissa A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869105/
https://ncbi.nlm.nih.gov/pubmed/20197421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00091.2009
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