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Intermittent and sustained hypoxia induce a similar gene expression profile in human aortic endothelial cells

Obstructive sleep apnea may cause vascular inflammation and atherosclerosis, which has been attributed to intermittent hypoxia (IH). Recent data suggest that IH, but not sustained hypoxia (SH), activates proinflammatory genes in HeLa cells. Effects of IH and SH on the gene expression profile in huma...

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Hlavní autoři: Polotsky, Vsevolod Y., Savransky, Vladimir, Bevans-Fonti, Shannon, Reinke, Christian, Li, Jianguo, Grigoryev, Dmitry N., Shimoda, Larissa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869105/
https://ncbi.nlm.nih.gov/pubmed/20197421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00091.2009
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