Chronic Intermittent Hypoxia and Acetaminophen Induce Synergistic Liver Injury

Obstructive sleep apnea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. OSA has been associated with liver injury. Acetaminophen (APAP) is one of the most commonly used drugs, which has known hepatotoxicity. The goal of the present study was to examine whether CIH increases liver inj...

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Bibliographic Details
Main Authors: Savransky, Vladimir, Reinke, Christian, Jun, Jonathan, Bevans-Fonti, Shannon, Nanayakkara, Ashika, Li, Jianguo, Myers, Allen C., Torbenson, Michael S., Polotsky, Vsevolod Y.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852632/
https://ncbi.nlm.nih.gov/pubmed/19028810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2008.044883
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