Chronic Intermittent Hypoxia and Acetaminophen Induce Synergistic Liver Injury

Obstructive sleep apnea (OSA) leads to chronic intermittent hypoxia (CIH) during sleep. OSA has been associated with liver injury. Acetaminophen (APAP) is one of the most commonly used drugs, which has known hepatotoxicity. The goal of the present study was to examine whether CIH increases liver inj...

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Autori principali: Savransky, Vladimir, Reinke, Christian, Jun, Jonathan, Bevans-Fonti, Shannon, Nanayakkara, Ashika, Li, Jianguo, Myers, Allen C., Torbenson, Michael S., Polotsky, Vsevolod Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852632/
https://ncbi.nlm.nih.gov/pubmed/19028810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2008.044883
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