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Structure-based development of specific inhibitors for individual cathepsins and their medical applications
Specific inhibitors for individual cathepsins have been developed based on their tertiary structures of X-ray crystallography. Cathepsin B-specific inhibitors, CA-074 and CA-030, and cathepsin L specific inhibitors, CLIK-148 and CLIK-195, were designed as the epoxysuccinate derivatives. Cathepsin S...
Tallennettuna:
| Päätekijä: | |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Japan Academy
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043741/ https://ncbi.nlm.nih.gov/pubmed/21321479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.87.29 |
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