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Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8(+) T Cell Response
T cell receptors (TCRs) mediate cytotoxic T lymphocyte (CTL) specificity, but TCRs recognizing the same epitope often differ between persons due to their stochastic derivation. The role of this variability in the pathogenesis of virus infections and malignancies has been technically difficult to stu...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043618/ https://ncbi.nlm.nih.gov/pubmed/20944001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002236 |
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