Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro.

We examined the roles of DNA topoisomerases in the replication of simian virus 40 (SV40) DNA in a cell-free system composed of an extract from HeLa cells supplemented with purified SV40 tumor antigen. When the activities of both topoisomerase I (EC 5.99.1.2) and topoisomerase II (EC 5.99.1.3) in the...

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Bibliographic Details
Main Authors: Yang, L, Wold, M S, Li, J J, Kelly, T J, Liu, L F
Format: Artigo
Language:Inglês
Published: 1987
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304337/
https://ncbi.nlm.nih.gov/pubmed/3029765
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