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VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease

Dopamine is transported into synaptic vesicles by the vesicular monoamine transporter (VMAT2; SLC18A2). Disruption of dopamine storage has been hypothesized to damage the dopamine neurons that are lost in Parkinson's disease. By disrupting vesicular storage of dopamine and other monoamines, we...

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Detalhes bibliográficos
Main Authors: Taylor, Tonya N., Caudle, W. Michael, Miller, Gary W.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043293/
https://ncbi.nlm.nih.gov/pubmed/21403896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/124165
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