Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease

BACKGROUND: The objective of this study was to determine whether neurotoxic kynurenine metabolites, induced by inflammation, in plasma and cerebrospinal fluid (CSF) are associated with symptom severity and nigral pathology in Parkinson's disease (PD). METHODS: Clinical and MRI data were obtaine...

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Bibliografski detalji
Izdano u:Mov Disord
Glavni autori: Heilman, Patrick L., Wang, Ernest W., Lewis, Mechelle M., Krzyzanowski, Stanislaw, Capan, Colt D., Burmeister, Amanda R., Du, Guangwei, Escobar Galvis, Martha L., Brundin, Patrik, Huang, Xuemei, Brundin, Lena
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Regular Issue Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754343/
https://ncbi.nlm.nih.gov/pubmed/32710594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28202
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