Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease

BACKGROUND: The objective of this study was to determine whether neurotoxic kynurenine metabolites, induced by inflammation, in plasma and cerebrospinal fluid (CSF) are associated with symptom severity and nigral pathology in Parkinson's disease (PD). METHODS: Clinical and MRI data were obtaine...

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Vydáno v:Mov Disord
Hlavní autoři: Heilman, Patrick L., Wang, Ernest W., Lewis, Mechelle M., Krzyzanowski, Stanislaw, Capan, Colt D., Burmeister, Amanda R., Du, Guangwei, Escobar Galvis, Martha L., Brundin, Patrik, Huang, Xuemei, Brundin, Lena
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
Regular Issue Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754343/
https://ncbi.nlm.nih.gov/pubmed/32710594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.28202
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