Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson’s disease

Abstract We previously demonstrated that kynurenine pathway (KP) dysregulation associates with Parkinson’s disease (PD) and its symptoms. Here, we profiled 16 KP-related markers in a second, independent cohort; plasma: n = 202 (116 PD (“OFF”), 86 controls); CSF: n = 183 (108, 75). Consistent with pr...

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Detalhes bibliográficos

Principais autores:	Leslie C. Jellen, Martha L. Escobar Galvis, Qiong Sha, Christine Isaguirre, Amy Johnson, Zach Madaj, Mechelle M. Lewis, Ryan D. Sheldon, Lan Kong, Xuemei Huang, Lena Brundin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-05-01
coleção:	npj Parkinson's Disease
Acesso em linha:	https://doi.org/10.1038/s41531-025-00949-6
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