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VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease
Dopamine is transported into synaptic vesicles by the vesicular monoamine transporter (VMAT2; SLC18A2). Disruption of dopamine storage has been hypothesized to damage the dopamine neurons that are lost in Parkinson's disease. By disrupting vesicular storage of dopamine and other monoamines, we...
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Glavni autori: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
SAGE-Hindawi Access to Research
2011
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043293/ https://ncbi.nlm.nih.gov/pubmed/21403896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/124165 |
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