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Phase I and pharmacologic study of BNP7787, a novel chemoprotector in patients with advanced non-small cell lung cancer

PURPOSE: We conducted a phase I trial of BNP7787 (disodium 2,2′-dithio-bis-ethane sulfonate, Tavocept™), a novel chemoprotective and antitumor enhancing agent administered in combination with paclitaxel and cisplatin. The primary aim was to determine a safe and potentially efficacious BNP7787 dose f...

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Bibliografiske detaljer
Main Authors: Masuda, Noriyuki, Negoro, Shunichi, Hausheer, Frederick, Nakagawa, Kazuhiko, Matsui, Kaoru, Kudoh, Shinzoh, Takeda, Koji, Yamamoto, Nobuyuki, Yoshimura, Naruo, Ohashi, Yasuo, Fukuoka, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043260/
https://ncbi.nlm.nih.gov/pubmed/20473611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1340-y
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