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Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2
In mammals, left-right (L-R) asymmetry is established by posteriorly oriented cilia driving a leftwards laminar flow in the embryonic node, thereby activating asymmetric gene expression. The two-cilia hypothesis argues that immotile cilia detect and respond to this flow through a Pkd2-mediated mecha...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042869/ https://ncbi.nlm.nih.gov/pubmed/21307093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058149 |
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