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Identification of a Chemical That Inhibits the Mycobacterial UvrABC Complex in Nucleotide Excision Repair
[Image: see text] Bacterial DNA can be damaged by reactive nitrogen and oxygen intermediates (RNI and ROI) generated by host immunity, as well as by antibiotics that trigger bacterial production of ROI. Thus a pathogen’s ability to repair its DNA may be important for persistent infection. A prominen...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042777/ https://ncbi.nlm.nih.gov/pubmed/21235228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101674c |
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