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Vascular endothelial growth factor-B gene transfer exacerbates retinal and choroidal neovascularization and vasopermeability without promoting inflammation

PURPOSE: The role of vascular endothelial growth factor (VEGF)-B in the eye is poorly understood. The present study was conducted to evaluate the effect of overexpression of VEGF-B via adeno-associated virus (AAV) gene transfer on ocular angiogenesis, inflammation, and the blood-retinal barrier (BRB...

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Detalhes bibliográficos
Main Authors: Zhong, Xiufeng, Huang, Hu, Shen, Jikui, Zacchigna, Serena, Zentilin, Lorena, Giacca, Mauro, Vinores, Stanley A.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042363/
https://ncbi.nlm.nih.gov/pubmed/21364963
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