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Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis
Pathogens that cause chronic infections often employ antigenic variation to evade the immune response and persist in the host. In Treponema pallidum (T. pallidum), the causative agent of syphilis, the TprK antigen undergoes variation of seven variable regions (V1-V7) by nonreciprocal recombination o...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042355/ https://ncbi.nlm.nih.gov/pubmed/20190145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902788 |
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