TprK Sequence Diversity Accumulates during Infection of Rabbits with Treponema pallidum subsp. pallidum Nichols Strain

The tprK gene in Treponema pallidum undergoes antigenic variation. In all T. pallidum isolates examined to date, except the Nichols type strain, heterogeneous tprK sequences have been identified. This heterogeneity is localized to seven variable (V) regions, and tprK sequence diversity accumulates w...

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Detalhes bibliográficos
Main Authors: LaFond, Rebecca E., Centurion-Lara, Arturo, Godornes, Charmie, Van Voorhis, Wesley C., Lukehart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1418662/
https://ncbi.nlm.nih.gov/pubmed/16495565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.3.1896-1906.2006
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