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S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice

A decrease of brain allopregnanolone biosynthesis may play a role in emotion, impulsive behavior, and anxiety spectrum disorders by decreasing GABAergic neurotransmission. In male mice, four weeks of social isolation induces behavioral dysfunctions such as aggression, fear, and anxiety-like behavior...

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Bibliographic Details
Main Authors: Nelson, Marianela, Pinna, Graziano
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042033/
https://ncbi.nlm.nih.gov/pubmed/20971127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.10.011
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