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Solving the shugoshin puzzle
Shugoshin proteins form a complex with protein phosphatase 2A (PP2A) that protects centromeric cohesin from separase-mediated cleavage during yeast meiosis I. Recent work shows that this mechanism is conserved from yeast to mammals. Importantly, a model emerges that explains a long-standing puzzle,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041985/ https://ncbi.nlm.nih.gov/pubmed/18378037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2008.02.001 |
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