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CLU blocks HDACI-mediated killing of neuroblastoma
Clusterin is a ubiquitously expressed glycoprotein with multiple binding partners including IL-6, Ku70, and Bax. Clusterin blocks apoptosis by binding to activated Bax and sequestering it in the cytoplasm, thereby preventing Bax from entering mitochondria, releasing cytochrome c, and triggering apop...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Netherlands
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041908/ https://ncbi.nlm.nih.gov/pubmed/21042904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13277-010-0120-y |
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