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Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy and constitutes 15% of adult leukemias. Although overall prognosis for pediatric ALL is favorable, high-risk pediatric patients and most adult patients have significantly worse outcomes. Multi-agent chemotherapy is standard o...

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Detalhes bibliográficos
Main Authors: Chao, Mark P., Alizadeh, Ash A., Tang, Chad, Jan, Max, Weissman-Tsukamoto, Rachel, Zhao, Feifei, Park, Christopher Y., Weissman, Irving L., Majeti, Ravindra
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041855/
https://ncbi.nlm.nih.gov/pubmed/21177380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2238
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