A Selective Matrix Metalloproteinase-12 Inhibitor Retards Atherosclerotic Plaque Development in Apolipoprotein E–Knockout Mice

OBJECTIVE: Matrix metalloproteinase (MMP)-12 has been implicated in plaque progression and instability and is also amenable to selective inhibition. In this study, we investigated the influence of a greater than 10-fold selective synthetic MMP-12 inhibitor on plaque progression in the apolipoprotein...

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מידע ביבליוגרפי
Main Authors: Johnson, Jason L., Devel, Laurent, Czarny, Bertrand, George, Sarah J., Jackson, Christopher L., Rogakos, Vassilis, Beau, Fabrice, Yiotakis, Athanasios, Newby, Andrew C., Dive, Vincent
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041652/
https://ncbi.nlm.nih.gov/pubmed/21212406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.219147
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