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Lipid oxidation by hypochlorous acid: chlorinated lipids in atherosclerosis and myocardial ischemia
Leukocytes, containing myeloperoxidase (MPO), produce the reactive chlorinating species, HOCl, and they have important roles in the pathophysiology of cardiovascular disease. Leukocyte-derived HOCl can target primary amines, alkenes and vinyl ethers of lipids, resulting in chlorinated products. Plas...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041592/ https://ncbi.nlm.nih.gov/pubmed/21339854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/clp.10.68 |
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