ω-Oxidation of α-Chlorinated Fatty Acids: IDENTIFICATION OF α-CHLORINATED DICARBOXYLIC ACIDS

Myeloperoxidase-derived HOCl targets tissue- and lipoprotein-associated plasmalogens to generate α-chlorinated fatty aldehydes, including 2-chlorohexadecanal. Under physiological conditions, 2-chlorohexadecanal is oxidized to 2-chlorohexadecanoic acid (2-ClHA). This study demonstrates the catabolism...

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Detalhes bibliográficos
Main Authors: Brahmbhatt, Viral V., Albert, Carolyn J., Anbukumar, Dhanalakshmi S., Cunningham, Bryce A., Neumann, William L., Ford, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009851/
https://ncbi.nlm.nih.gov/pubmed/20956542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147157
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