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Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by changes in microsomal cholesterol content or phospholipid composition.

Microsomal preparations from normal human skin fibroblasts were used to investigate the role of free cholesterol in the endoplasmic reticulum in the control of cholesterol biosynthesis by regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (NADPH) [(S)-mevalonate:NADP+ oxidoreductase (CoA-...

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Bibliografische gegevens
Hoofdauteurs: Davis, P J, Poznansky, M J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1987
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC304153/
https://ncbi.nlm.nih.gov/pubmed/3467343
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