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Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by changes in microsomal cholesterol content or phospholipid composition.

Microsomal preparations from normal human skin fibroblasts were used to investigate the role of free cholesterol in the endoplasmic reticulum in the control of cholesterol biosynthesis by regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (NADPH) [(S)-mevalonate:NADP+ oxidoreductase (CoA-...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Davis, P J, Poznansky, M J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1987
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3467343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.118
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