A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli

Bacterial artificial chromosomes (BACs) and P1 artificial chromosomes (PACs), which contain large fragments of genomic DNA, have been successfully used as transgenes to create mouse models of dose-dependent diseases. They are also potentially valuable as transgenes for dominant diseases given that p...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Lalioti, Maria D., Heath, John K.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2001
Témata:	NAR Methods Online
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160916/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.e14
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