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Glycosylation affects cleavage of an H5N2 influenza virus hemagglutinin and regulates virulence.

Based on nucleotide sequence analysis of the hemagglutinin (HA) gene from the virulent and avirulent A/chicken/Pennsylvania/83 influenza viruses, it was previously postulated that acquisition of virulence was associated with a point mutation that resulted in loss of a glycosylation site. Since there...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Deshpande, K L, Fried, V A, Ando, M, Webster, R G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1987
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3467357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.36
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