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Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus

2-Arachidonoylglycerol (2-AG) is the endocannabinoid that mediates retrograde suppression of synaptic transmission in the brain. 2-AG is synthesized in activated postsynaptic neurons by sn-1-specific diacylglycerol lipase (DGL), binds to presynaptic cannabinoid CB(1) receptors, suppresses neurotrans...

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Detalhes bibliográficos
Main Authors: Yoshida, Takayuki, Uchigashima, Motokazu, Yamasaki, Miwako, Katona, Istvan, Yamazaki, Maya, Sakimura, Kenji, Kano, Masanobu, Yoshioka, Mitsuhiro, Watanabe, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041100/
https://ncbi.nlm.nih.gov/pubmed/21282604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012875108
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