Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression

The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates retrograde synaptic suppression. Although the mechanisms of 2-AG production are well characterized, how 2-AG is degraded is less clearly understood. Here we found that expression of the 2-AG hydrolyzing enzyme monoacylglycerol lipase (MGL) w...

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Bibliografiset tiedot
Päätekijät: Tanimura, Asami, Uchigashima, Motokazu, Yamazaki, Maya, Uesaka, Naofumi, Mikuni, Takayasu, Abe, Manabu, Hashimoto, Kouichi, Watanabe, Masahiko, Sakimura, Kenji, Kano, Masanobu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409771/
https://ncbi.nlm.nih.gov/pubmed/22783023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204404109
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