Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression

The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates retrograde synaptic suppression. Although the mechanisms of 2-AG production are well characterized, how 2-AG is degraded is less clearly understood. Here we found that expression of the 2-AG hydrolyzing enzyme monoacylglycerol lipase (MGL) w...

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Detalhes bibliográficos
Main Authors: Tanimura, Asami, Uchigashima, Motokazu, Yamazaki, Maya, Uesaka, Naofumi, Mikuni, Takayasu, Abe, Manabu, Hashimoto, Kouichi, Watanabe, Masahiko, Sakimura, Kenji, Kano, Masanobu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409771/
https://ncbi.nlm.nih.gov/pubmed/22783023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204404109
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