Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse elimination

In Purkinje cells (PCs) of the cerebellum, a single “winner” climbing fiber (CF) monopolizes proximal dendrites, whereas hundreds of thousands of parallel fibers (PFs) innervate distal dendrites, and both CF and PF inputs innervate a narrow intermediate domain. It is unclear how this segregated CF a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Ichikawa, Ryoichi, Hashimoto, Kouichi, Miyazaki, Taisuke, Uchigashima, Motokazu, Yamasaki, Miwako, Aiba, Atsu, Kano, Masanobu, Watanabe, Masahiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776453/
https://ncbi.nlm.nih.gov/pubmed/26858447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511513113
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