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Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59

Clinical studies have indicated that subvirion inactivated vaccines against avian influenza viruses, particularly H5N1, are poorly immunogenic in humans. As a consequence, the use of adjuvants has been championed for the efficient vaccination of a naïve population against avian influenza. Aluminum s...

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Bibliografiske detaljer
Main Authors: Ellebedy, Ali H., Lupfer, Christopher, Ghoneim, Hazem E., DeBeauchamp, Jennifer, Kanneganti, Thirumala-Devi, Webby, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041074/
https://ncbi.nlm.nih.gov/pubmed/21270336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012455108
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