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Flow Cytometry: A Promising Technique for the Study of Silicone Oil-Induced Particulate Formation in Protein Formulations

Subvisible particles in formulations intended for parenteral administration are of concern in the biopharmaceutical industry. However, monitoring and control of subvisible particulates can be complicated by formulation components, such as the silicone oil used for the lubrication of prefilled syring...

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Detalhes bibliográficos
Main Authors: Ludwig, D. Brett, Trotter, Joseph T., Gabrielson, John P., Carpenter, John F., Randolph, Theodore W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040987/
https://ncbi.nlm.nih.gov/pubmed/21146492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.12.008
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