Prioritization of driver mutations in pancreatic cancer using cancer-specific high-throughput annotation of somatic mutations (CHASM)

Over 20,000 genes were recently sequenced in a series of 24 pancreatic cancers. We applied CHASM (Cancer-specific High-throughput Annotation of Somatic Mutations) to 963 of the missense somatic missense mutations discovered in these 24 cancers. CHASM identified putative driver mutations (false disco...

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Bibliografiske detaljer
Main Authors: Carter, Hannah, Samayoa, Josue, Hruban, Ralph H, Karchin, Rachel
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040948/
https://ncbi.nlm.nih.gov/pubmed/20581473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.6.12537
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