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CHASM and SNVBox: toolkit for detecting biologically important single nucleotide mutations in cancer

Summary: Thousands of cancer exomes are currently being sequenced, yielding millions of non-synonymous single nucleotide variants (SNVs) of possible relevance to disease etiology. Here, we provide a software toolkit to prioritize SNVs based on their predicted contribution to tumorigenesis. It includ...

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Hlavní autoři: Wong, Wing Chung, Kim, Dewey, Carter, Hannah, Diekhans, Mark, Ryan, Michael C., Karchin, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137226/
https://ncbi.nlm.nih.gov/pubmed/21685053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr357
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