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Tumor suppressor p53 status does not determine the differentiation-associated G(1) cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D(3) and antioxidants

Vitamin D derivatives can induce differentiation of human acute myeloid leukemia (AML) cells. Here, we investigated if the G(1) cell cycle block associated with monocytic differentiation is modulated by the p53 status of the cells treated with 1,25D, alone or with plant antioxidants carnosic acid (C...

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Detalhes bibliográficos
Main Authors: Thompson, Thelma, Danilenko, Michael, Vassilev, Lyubomir, Studzinski, George P
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040853/
https://ncbi.nlm.nih.gov/pubmed/20543580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.4.12366
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