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Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis
O-linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc addition to numerous cellular proteins including transcription and nuclear pore complexes and plays a key role in cellular signaling. One differentially spliced isoform of OGT is normally targeted to mitochondria (mOGT) but is quite c...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Vienna
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040817/ https://ncbi.nlm.nih.gov/pubmed/20824293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0719-8 |
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