Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes

BACKGROUND: Several approaches have been developed for miRNA target prediction, including methods that incorporate expression profiling. However the methods are still in need of improvements due to a high false discovery rate. So far, none of the methods have used independent component analysis (ICA...

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Bibliographic Details
Main Authors: Bang-Berthelsen, Claus H, Pedersen, Lykke, Fløyel, Tina, Hagedorn, Peter H, Gylvin, Titus, Pociot, Flemming
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040732/
https://ncbi.nlm.nih.gov/pubmed/21294859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-97
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