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Characterization of the past and current duplication activities in the human 22q11.2 region

BACKGROUND: Segmental duplications (SDs) on 22q11.2 (LCR22), serve as substrates for meiotic non-allelic homologous recombination (NAHR) events resulting in several clinically significant genomic disorders. RESULTS: To understand the duplication activity leading to the complicated SD structure of th...

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Библиографические подробности
Главные авторы: Guo, Xingyi, Freyer, Laina, Morrow, Bernice, Zheng, Deyou
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040729/
https://ncbi.nlm.nih.gov/pubmed/21269513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-71
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