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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
Tumour cells release an abundance of microvesicles containing a selected set of proteins and RNAs. Here, we show that tumour microvesicles also carry DNA, which reflects the genetic status of the tumour, including amplification of the oncogene c-Myc. We also find amplified c-Myc in serum microvesicl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040683/ https://ncbi.nlm.nih.gov/pubmed/21285958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1180 |
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