Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila

The intracellular bacterial pathogen Legionella pneumophila causes an inflammatory pneumonia called Legionnaires' Disease. For virulence, L. pneumophila requires a Dot/Icm type IV secretion system that translocates bacterial effectors to the host cytosol. L. pneumophila lacking the Dot/Icm syst...

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Bibliographische Detailangaben
Hauptverfasser: Fontana, Mary F., Banga, Simran, Barry, Kevin C., Shen, Xihui, Tan, Yunhao, Luo, Zhao-Qing, Vance, Russell E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040669/
https://ncbi.nlm.nih.gov/pubmed/21390206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001289
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