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Interleukin-1α signaling initiates the inflammatory response to virulent Legionella pneumophila in vivo

Legionella pneumophila is an intracellular bacterial pathogen that is the cause of a severe pneumonia in humans called Legionnaires’ Disease. A key feature of L. pneumophila pathogenesis is the rapid influx of neutrophils into the lungs, which occurs in response to signaling via the interleukin-1 re...

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Detalhes bibliográficos
Main Authors: Barry, Kevin C., Fontana, Mary F., Portman, Jonathan L., Dugan, Aisling S., Vance, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682686/
https://ncbi.nlm.nih.gov/pubmed/23686480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300100
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