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Brain mitochondria from rats treated with sulforaphane are resistant to redox-regulated permeability transition
Oxidative stress promotes Ca(2+)-dependent opening of the mitochondrial inner membrane permeability transition pore (PTP), causing bioenergetic failure and subsequent cell death in many paradigms, including those related to acute brain injury. One approach to preconditioning against oxidative stress...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040633/ https://ncbi.nlm.nih.gov/pubmed/21061051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-010-9312-9 |
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